STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rce1CAAX prenyl protease 2 {ECO:0000305|}; Endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine, A is an aliphatic amino acid and X is any amino acid. Cleaves the CAAX motif C-terminal to both P1 and P1' positions. Hydrolysis depends on a farnesylated cysteine residue and no activity is shown towards geranylgeranylated peptides. inhibitors 5 mM EDTA and 5 mM Zn(2+). Activity partially inhibited by 1,10-phenanthroline and 1,7-phenanthroline. Kinetic parameters: KM=19.7 uM for peptide substrate DABCYL [...] (176 aa)    
Predicted Functional Partners:
SCM57307.1
Putative protein {ECO:0000313|EMBL:AAB85129,1}; tr|O26720|O26720_METTH;evalue=2e-028; PctID=69.51; score=130.
      0.930
SCM57987.1
Putative protein MTH_987; sp|O27068|Y987_METTH;evalue=2e-155; PctID=72.70; score=549.
  
  
 0.724
SCM57903.1
Putative protein {ECO:0000313|EMBL:AAB85431,1}; tr|O27016|O27016_METTH,tr|T2GHR6|T2GHR6_9EURY; evalue=1e-093; PctID=69.14; score=349.
 
  
 0.707
kefC
Glutathione-regulated potassium-efflux system protein KefC {ECO:0000255|HAMAP-Rule:MF_01413}; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. Rule:MF_01413}; Multi-pass membrane protein (CPA2) transporter (TC 2.A.37) family. KefC subfamily. Rule:MF_01413}; sp|B4TJ42|KEFC_SALHS;evalue=9e-052; PctID=26.73; score=205.
  
  
 0.673
SCM57616.1
Putative protein {ECO:0000313|EMBL:AAB85291,1}; tr|O26882|O26882_METTH;evalue=4e-060; PctID=51.52; score=237.
  
    0.654
SCM57309.1
Hypothetical protein.
       0.617
SCM56466.1
Putative nitroreductase MJ1384; sp|Q58779|Y1384_METJA;evalue=6e-023; PctID=32.29; score=107.
 
  
 0.604
yadH
Predicted ABC transporter, permease component; Hypothetical protein.
  
 
 0.579
ycf38
Putative transport permease ycf38; sp|P48278|YCF38_CYAPA;evalue=1e-020; PctID=31.16; score=100.
  
 
 0.579
SCM56475.1
Putative NADH dehydrogenase/NAD(P)H nitroreductase; sp|O26223|Y120_METTH;evalue=1e-084; PctID=84.02; score=311.
  
  
 0.507
Your Current Organism:
Methanothermobacter wolfeii
NCBI taxonomy Id: 145261
Other names: ATCC 43096, DSM 2970, JCM 14652, M. wolfeii, Methanobacterium wolfei, Methanobacterium wolfeii, Methanothermobacter wolfei, NBRC 100332, OCM 154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.