Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCM55842.1 | SCM57963.1 | MWSIV6_0183 | MWSIV6_1360 | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | 0.965 |
| SCM55842.1 | pan | MWSIV6_0183 | MWSIV6_1103 | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | Proteasome-activating nucleotidase {ECO:0000255|HAMAP-Rule:MF_00553}; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas [...] | 0.951 |
| SCM55842.1 | psmA | MWSIV6_0183 | MWSIV6_1062 | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | Proteasome subunit alpha {ECO:0000255|HAMAP-Rule:MF_00289}; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.897 |
| SCM55842.1 | psmB | MWSIV6_0183 | MWSIV6_1595 | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | Proteasome subunit beta {ECO:0000255|HAMAP-Rule:MF_02113}; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.893 |
| SCM55842.1 | rpl2 | MWSIV6_0183 | MWSIV6_0458 | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | 50S ribosomal protein L2 {ECO:0000255|HAMAP-Rule:MF_01320}; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.805 |
| SCM55842.1 | rpl40e | MWSIV6_0183 | MWSIV6_0918 | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | 50S ribosomal protein L40e {ECO:0000255|HAMAP-Rule:MF_00788}; sp|O26653|RL40_METTH;evalue=4e-023; PctID=100.00; score=106; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.971 |
| SCM57502.1 | pan | MWSIV6_1104 | MWSIV6_1103 | Putative HTH-type transcriptional regulator MJ0586; sp|Q58006|Y586_METJA;evalue=5e-010; PctID=40.91; score=63.5. | Proteasome-activating nucleotidase {ECO:0000255|HAMAP-Rule:MF_00553}; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas [...] | 0.803 |
| SCM57502.1 | rpl2 | MWSIV6_1104 | MWSIV6_0458 | Putative HTH-type transcriptional regulator MJ0586; sp|Q58006|Y586_METJA;evalue=5e-010; PctID=40.91; score=63.5. | 50S ribosomal protein L2 {ECO:0000255|HAMAP-Rule:MF_01320}; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.875 |
| SCM57502.1 | rpl40e | MWSIV6_1104 | MWSIV6_0918 | Putative HTH-type transcriptional regulator MJ0586; sp|Q58006|Y586_METJA;evalue=5e-010; PctID=40.91; score=63.5. | 50S ribosomal protein L40e {ECO:0000255|HAMAP-Rule:MF_00788}; sp|O26653|RL40_METTH;evalue=4e-023; PctID=100.00; score=106; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.872 |
| SCM57502.1 | tgtA | MWSIV6_1104 | MWSIV6_0592 | Putative HTH-type transcriptional regulator MJ0586; sp|Q58006|Y586_METJA;evalue=5e-010; PctID=40.91; score=63.5. | tRNA-guanine(15) transglycosylase {ECO:0000255|HAMAP-Rule:MF_01634}; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.816 |
| SCM57963.1 | SCM55842.1 | MWSIV6_1360 | MWSIV6_0183 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | 0.965 |
| SCM57963.1 | pan | MWSIV6_1360 | MWSIV6_1103 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | Proteasome-activating nucleotidase {ECO:0000255|HAMAP-Rule:MF_00553}; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas [...] | 0.998 |
| SCM57963.1 | psmA | MWSIV6_1360 | MWSIV6_1062 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | Proteasome subunit alpha {ECO:0000255|HAMAP-Rule:MF_00289}; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.953 |
| SCM57963.1 | psmB | MWSIV6_1360 | MWSIV6_1595 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | Proteasome subunit beta {ECO:0000255|HAMAP-Rule:MF_02113}; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.953 |
| SCM57963.1 | rad50 | MWSIV6_1360 | MWSIV6_0905 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per homodimer; subunits and two Rad50 subunits. hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zi [...] | 0.634 |
| SCM57963.1 | rpl2 | MWSIV6_1360 | MWSIV6_0458 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | 50S ribosomal protein L2 {ECO:0000255|HAMAP-Rule:MF_01320}; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.498 |
| SCM57963.1 | rpl40e | MWSIV6_1360 | MWSIV6_0918 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | 50S ribosomal protein L40e {ECO:0000255|HAMAP-Rule:MF_00788}; sp|O26653|RL40_METTH;evalue=4e-023; PctID=100.00; score=106; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.990 |
| SCM57963.1 | tuf | MWSIV6_1360 | MWSIV6_1444 | Putative metalloprotease HVO_1016; Probable metalloprotease. Does not hydrolyze SAMP1-and SAMP2-protein conjugates, diglycine-AMC, Ub-AMC, hemoglobin, cytochrome c, carbonic anhydrase, creatinine phosphokinase, beta-amylase and bovine serum albumin. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit; sp|D4GVJ3|JAMM2_HALVD;evalue=1e-008; PctID=30.88; score=58.5. | Elongation factor 1-alpha {ECO:0000255|HAMAP-Rule:MF_00118}; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.453 |
| pan | SCM55842.1 | MWSIV6_1103 | MWSIV6_0183 | Proteasome-activating nucleotidase {ECO:0000255|HAMAP-Rule:MF_00553}; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas [...] | ATPase; AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; Hypothetical protein. | 0.951 |
| pan | SCM57502.1 | MWSIV6_1103 | MWSIV6_1104 | Proteasome-activating nucleotidase {ECO:0000255|HAMAP-Rule:MF_00553}; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas [...] | Putative HTH-type transcriptional regulator MJ0586; sp|Q58006|Y586_METJA;evalue=5e-010; PctID=40.91; score=63.5. | 0.803 |
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