STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCM57626.1Conserved protein {ECO:0000313|EMBL:AAB85295,1}; tr|O26886|O26886_METTH;evalue=4e-139; PctID=62.73; score=501. (401 aa)    
Predicted Functional Partners:
SCM57628.1
Conserved protein {ECO:0000313|EMBL:AAB85296,1}; tr|O26887|O26887_METTH;evalue=1e-047; PctID=60.84; score=195.
       0.575
uvrB
UvrABC system protein B {ECO:0000255|HAMAP-Rule:MF_00204}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is foun [...]
    
 0.489
uvrC
UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.467
uvrA
UvrABC system protein A {ECO:0000255|HAMAP-Rule:MF_00205}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
    
  0.455
SCM57624.1
Hypothetical protein.
       0.444
thsB
Thermosome subunit beta; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity. membered rings; sp|O26885|THSB_METTH;evalue=0.0; PctID=95.74; score=941; Belongs to the TCP-1 chaperonin family.
     
 0.415
SCM56135.1
ATPase {ECO:0000313|EMBL:BAM70902,1}; tr|T2GKB7|T2GKB7_9EURY;evalue=3e-128; PctID=80.07; score=464.
 
  
 0.408
Your Current Organism:
Methanothermobacter wolfeii
NCBI taxonomy Id: 145261
Other names: ATCC 43096, DSM 2970, JCM 14652, M. wolfeii, Methanobacterium wolfei, Methanobacterium wolfeii, Methanothermobacter wolfei, NBRC 100332, OCM 154
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