STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phrDeoxyribodipyrimidine photo-lyase; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. residues (in DNA). Name=FAD; Xref=ChEBI:CHEBI:57692; Note=Binds 1 FAD per subunit; Name=oxidized coenzyme F420; Xref=ChEBI:CHEBI:57922; Note=Binds 1 coenzyme F420 non-covalently per subunit; sp|P12769|PHR_METTH;evalue=0.0; PctID=69.91; score=653. (454 aa)    
Predicted Functional Partners:
SCM57817.1
Putative protein {ECO:0000313|EMBL:ADL58885,1}; tr|D9PXD7|D9PXD7_METTM;evalue=5e-130; PctID=73.16; score=470.
 
  
 0.870
sod
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
   0.834
arsC
Protein ArsC {ECO:0000255|HAMAP-Rule:MF_01624}; Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances. tyrosine + phosphate. thioredoxin disulfide + H(2)O. protein phosphatase superfamily. ArsC family; sp|B9E7M5|ARSC_MACCJ;evalue=9e-020; PctID=42.02; score=95.5.
   
 
 0.796
infB
Putative translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
    
   0.784
SCM58188.1
Metallo-beta- lactamase{ECO:0000313|EMBL:BAM70238,1}; tr|T2GKS7|T2GKS7_9EURY;evalue=4e-016; PctID=80.77; score=89.7.
   
 
 0.780
SCM58190.1
Putative hydrolase {ECO:0000313|EMBL:ADL59060,1}; tr|D9PXW2|D9PXW2_METTM;evalue=0.0; PctID=77.17; score=659.
   
 
 0.780
rps17p
30S ribosomal protein S17P {ECO:0000255|HAMAP-Rule:MF_01345}; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
    
   0.767
nucS
Endonuclease NucS {ECO:0000255|HAMAP-Rule:MF_00722}; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
      
 0.702
uvrC
UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.650
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
     
 0.641
Your Current Organism:
Methanothermobacter wolfeii
NCBI taxonomy Id: 145261
Other names: ATCC 43096, DSM 2970, JCM 14652, M. wolfeii, Methanobacterium wolfei, Methanobacterium wolfeii, Methanothermobacter wolfei, NBRC 100332, OCM 154
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