STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT05_00650Magnesium transporter; Acts as a magnesium transporter. (459 aa)    
Predicted Functional Partners:
AT05_00645
Magnesium transporter MgtC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.801
AT05_00655
Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.738
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.738
guaB
Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.617
AT05_10015
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 5'-nucleotidase family.
    
  0.494
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.470
AT05_00640
Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.460
AT05_02595
Deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.446
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.446
AT05_00660
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.429
Your Current Organism:
Schleiferia thermophila
NCBI taxonomy Id: 1453500
Other names: S. thermophila str. Yellowstone, Schleiferia thermophila str. Yellowstone
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