STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT05_04105Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (936 aa)    
Predicted Functional Partners:
AT05_04100
Glutamate:proton symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.773
AT05_06810
beta-N-acetylglucosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.745
AT05_04160
Elongation factor Tu; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.706
AT05_08170
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.705
AT05_10795
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
    0.704
AT05_06225
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.689
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
       0.686
AT05_07060
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.651
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.649
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.645
Your Current Organism:
Schleiferia thermophila
NCBI taxonomy Id: 1453500
Other names: S. thermophila str. Yellowstone, Schleiferia thermophila str. Yellowstone
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