STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1129 aa)    
Predicted Functional Partners:
AT05_00145
methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.999
AT05_00150
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.942
AT05_07455
4-hydroxybutyrate CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
AT05_07275
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.893
AT05_04875
Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
0.840
AT05_03515
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.832
AT05_03855
Phenylacetic acid degradation protein PaaN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.823
AT05_05940
Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.810
sucD
succinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.798
AT05_03710
4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.795
Your Current Organism:
Schleiferia thermophila
NCBI taxonomy Id: 1453500
Other names: S. thermophila str. Yellowstone, Schleiferia thermophila str. Yellowstone
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