STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MNEG_2916Cyclin-A1; Belongs to the cyclin family. (306 aa)    
Predicted Functional Partners:
MNEG_8110
Uncharacterized protein.
   
 0.889
MNEG_12626
Cyclin-dependent kinase B1-21.
  
 0.845
MNEG_8180
DUF3452 domain-containing protein.
   
 0.836
MNEG_11782
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.830
MNEG_12374
Cyclin-dependent kinase 3.
  
 0.792
MNEG_5754
Protein kinase domain-containing protein.
   
 0.782
MNEG_9980
Mitotic spindle assembly checkpoint protein MAD2A.
   
 
 0.740
MNEG_8369
Uncharacterized protein.
    
 0.726
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.712
MNEG_2026
Putative Cell division cycle protein 20.
   
 0.709
Your Current Organism:
Monoraphidium neglectum
NCBI taxonomy Id: 145388
Other names: M. neglectum, Monoraphidium neglectum Heynig & Krienitz, SAG 48.87
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