node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | MNEG_10867 | A0A0D2ML14 | A0A0D2M0D8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | 0.712 |
MCM7 | MNEG_11782 | A0A0D2ML14 | A0A0D2MN78 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. | 0.430 |
MCM7 | MNEG_12374 | A0A0D2ML14 | A0A0D2J725 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cyclin-dependent kinase 3. | 0.730 |
MCM7 | MNEG_12626 | A0A0D2ML14 | A0A0D2KHP0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cyclin-dependent kinase B1-21. | 0.730 |
MCM7 | MNEG_2026 | A0A0D2ML14 | A0A0D2LHF4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Putative Cell division cycle protein 20. | 0.511 |
MCM7 | MNEG_8110 | A0A0D2ML14 | A0A0D2M980 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.996 |
MCM7 | MNEG_8180 | A0A0D2ML14 | A0A0D2KWY4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DUF3452 domain-containing protein. | 0.599 |
MCM7 | MNEG_9980 | A0A0D2ML14 | A0A0D2MU67 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Mitotic spindle assembly checkpoint protein MAD2A. | 0.620 |
MNEG_10867 | MCM7 | A0A0D2M0D8 | A0A0D2ML14 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.712 |
MNEG_10867 | MNEG_11782 | A0A0D2M0D8 | A0A0D2MN78 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. | 0.830 |
MNEG_10867 | MNEG_12374 | A0A0D2M0D8 | A0A0D2J725 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Cyclin-dependent kinase 3. | 0.768 |
MNEG_10867 | MNEG_12626 | A0A0D2M0D8 | A0A0D2KHP0 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Cyclin-dependent kinase B1-21. | 0.810 |
MNEG_10867 | MNEG_2026 | A0A0D2M0D8 | A0A0D2LHF4 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Putative Cell division cycle protein 20. | 0.709 |
MNEG_10867 | MNEG_5754 | A0A0D2M0D8 | A0A0D2MNY2 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Protein kinase domain-containing protein. | 0.756 |
MNEG_10867 | MNEG_8110 | A0A0D2M0D8 | A0A0D2M980 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Uncharacterized protein. | 0.862 |
MNEG_10867 | MNEG_8180 | A0A0D2M0D8 | A0A0D2KWY4 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | DUF3452 domain-containing protein. | 0.830 |
MNEG_10867 | MNEG_8369 | A0A0D2M0D8 | A0A0D2MFY9 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Uncharacterized protein. | 0.726 |
MNEG_10867 | MNEG_9980 | A0A0D2M0D8 | A0A0D2MU67 | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | Mitotic spindle assembly checkpoint protein MAD2A. | 0.740 |
MNEG_11782 | MCM7 | A0A0D2MN78 | A0A0D2ML14 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.430 |
MNEG_11782 | MNEG_10867 | A0A0D2MN78 | A0A0D2M0D8 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. | G2/mitotic-specific cyclin-A; Belongs to the cyclin family. | 0.830 |