STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (703 aa)    
Predicted Functional Partners:
NMS_0467
ATP-dependent DNA ligase.
     
 0.919
NMS_0666
leucyl-tRNA synthetase.
  
 
 
 0.829
NMS_2771
ATP-dependent DNA helicase UvrD/PcrA.
 
  
 0.803
NMS_0427
DNA polymerase III alpha subunit.
    
 0.791
NMS_1863
Methylase of polypeptide chain release factors.
 
   
 0.776
NMS_0102
DNA polymerase III epsilon subunit.
  
 
 0.771
NMS_2392
DNA polymerase III epsilon subunit.
  
 
 0.771
NMS_1862
Uncharacterized acetyltransferase YjgM.
       0.722
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.718
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
   
 0.709
Your Current Organism:
Nonlabens marinus
NCBI taxonomy Id: 1454201
Other names: Flavobacteria bacterium S1-08, N. marinus S1-08, Nonlabens marinus S1-08
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.