STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SD78_3673Sporulation sigma-E factor processing peptidase (SpoIIGA); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. (308 aa)    
Predicted Functional Partners:
SD78_3674
RNA polymerase sporulation specific sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.952
SD78_1182
Stage II sporulation serine phosphatase for sigma-F activation (SpoIIE).
  
  
 0.946
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.906
SD78_0666
Stage II sporulation protein.
 
   
 0.873
SD78_3675
RNA polymerase sporulation specific sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.842
SD78_2272
Stage II sporulation protein M (SpoIIM); Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.
  
  
 0.815
SD78_3676
Hypothetical protein.
 
     0.814
SD78_3648
Membrane protein.
  
   
 0.800
SD78_2418
Stage IV sporulation protein.
  
   
 0.799
SD78_2419
Hypothetical protein.
  
  
 0.783
Your Current Organism:
Bacillus badius
NCBI taxonomy Id: 1455
Other names: ATCC 14574, B. badius, Bacillus encimensis, Bacillus encimensis Dastager et al. 2015, Bacillus sp. SGD-V-25, CCUG 7412, CIP 58.52, DSM 23, DSM 28241 [[Bacillus encimensis]], IFO 15713, JCM 12228, LMG 7122, LMG:7122, NBRC 15713, NCIB 9364, NCIB:9364, NCIM 5513, NCTC 10333, NRRL NRS-663, VKM B-496, strain SGD-V-25 [[Bacillus encimensis]]
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