STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdeA_1Methionine gamma-lyase. (401 aa)    
Predicted Functional Partners:
mccA
O-acetylserine dependent cystathionine beta-synthase.
 0.948
yitJ
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
  
 
 0.940
acsE
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
  
 
 0.921
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.920
trxB
Thioredoxin reductase.
   
 
 0.910
metG_1
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.910
msrC
Free methionine-R-sulfoxide reductase.
     
 0.901
OSB_10640
CoA binding domain protein.
 
      0.895
metZ
O-succinylhomoserine sulfhydrylase.
  
  
 
0.831
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.763
Your Current Organism:
Octadecabacter temperatus
NCBI taxonomy Id: 1458307
Other names: DSM 26878, LMG 27946, LMG:27946, O. temperatus, Octadecabacter sp. SB1, Octadecabacter temperatus Billerbeck et al. 2015, strain SB1
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