STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pucM5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (118 aa)    
Predicted Functional Partners:
pucL
Uric acid degradation bifunctional protein PucL.
  
 0.996
allA
Ureidoglycolate lyase.
 
    0.883
OSB_04080
Cytochrome c.
 
  
 0.862
xdhA
Xanthine dehydrogenase molybdenum-binding subunit.
 
  
 0.847
cdhC
Caffeine dehydrogenase subunit gamma.
 
     0.798
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.772
OSB_05460
XdhC and CoxI family protein.
 
     0.768
uacT
Uric acid transporter UacT.
 
  
 0.757
yedZ
Sulfoxide reductase heme-binding subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...]
   
    0.623
OSB_04190
Hypothetical protein.
 
   
 0.552
Your Current Organism:
Octadecabacter temperatus
NCBI taxonomy Id: 1458307
Other names: DSM 26878, LMG 27946, LMG:27946, O. temperatus, Octadecabacter sp. SB1, Octadecabacter temperatus Billerbeck et al. 2015, strain SB1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.