STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspC_2Aspartate aminotransferase. (390 aa)    
Predicted Functional Partners:
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
    0.859
ppiD
Peptidyl-prolyl cis-trans isomerase D.
       0.729
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
   
 
 0.664
rhtC_3
Threonine efflux protein.
       0.659
fabI_1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI.
       0.658
pdxH
Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
     
 0.548
gltB
Glutamate synthase [NADPH] large chain precursor.
  
  
 0.547
OSB_19540
Hypothetical protein.
  
     0.493
ywrO
General stress protein 14.
   
    0.453
OSB_16790
Indolepyruvate ferredoxin oxidoreductase.
 
   
 0.408
Your Current Organism:
Octadecabacter temperatus
NCBI taxonomy Id: 1458307
Other names: DSM 26878, LMG 27946, LMG:27946, O. temperatus, Octadecabacter sp. SB1, Octadecabacter temperatus Billerbeck et al. 2015, strain SB1
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