STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemA_25-aminolevulinate synthase. (407 aa)    
Predicted Functional Partners:
gcvT_1
Aminomethyltransferase; Belongs to the GcvT family.
  
 0.928
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.916
ltaE
Low specificity L-threonine aldolase.
   
 
 0.913
glyA1
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.910
OSB_33080
Fluorothreonine transaldolase.
  
 
 0.910
OSB_08310
Soluble hydrogenase 42 kDa subunit.
    
 0.906
hemA_1
5-aminolevulinate synthase.
  
  
 
0.902
soxB_1
Sarcosine oxidase subunit beta.
  
 
 0.901
OSB_12660
Sarcosine oxidase, delta subunit family.
     
  0.900
OSB_12680
Sarcosine oxidase, gamma subunit family.
     
  0.900
Your Current Organism:
Octadecabacter temperatus
NCBI taxonomy Id: 1458307
Other names: DSM 26878, LMG 27946, LMG:27946, O. temperatus, Octadecabacter sp. SB1, Octadecabacter temperatus Billerbeck et al. 2015, strain SB1
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