STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDO58936.1Acetyl-coenzyme A synthetase. (641 aa)    
Predicted Functional Partners:
CDO59827.1
NADP-dependent malic enzyme.
  
 0.910
CDO61055.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.873
CDO60174.1
Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35).
  
 
 0.824
CDO59044.1
Enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.824
CDO59711.1
Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative.
 
  
 0.820
CDO61157.1
Hydroxymethylglutaryl-CoA synthase.
  
 
 0.812
CDO59480.1
Methylmalonate-semialdehyde dehydrogenase.
   
  0.806
CDO59417.1
Biotin carboxylase.
  
 
 0.801
CDO58935.1
3-oxoacyl-[acyl-carrier protein] reductase.
    
  0.797
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.770
Your Current Organism:
Phaeomarinobacter ectocarpi
NCBI taxonomy Id: 1458461
Other names: C. Phaeomarinobacter ectocarpi, Candidatus Phaeomarinobacter ectocarpi, bacterium Ec32
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