node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCL13003.1 | SCL22403.1 | GA0070616_0095 | GA0070616_2530 | Tryptophan 2,3-dioxygenase. | Alpha/beta hydrolase family protein. | 0.775 |
SCL13003.1 | SCL25475.1 | GA0070616_0095 | GA0070616_3112 | Tryptophan 2,3-dioxygenase. | Selenocysteine lyase/Cysteine desulfurase. | 0.749 |
SCL13003.1 | SCL27693.1 | GA0070616_0095 | GA0070616_3550 | Tryptophan 2,3-dioxygenase. | Kynurenine formamidase. | 0.744 |
SCL13003.1 | kynA | GA0070616_0095 | GA0070616_1395 | Tryptophan 2,3-dioxygenase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.907 |
SCL13003.1 | kynU | GA0070616_0095 | GA0070616_0219 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.931 |
SCL13003.1 | kynU-2 | GA0070616_0095 | GA0070616_0533 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.930 |
SCL13003.1 | kynU-3 | GA0070616_0095 | GA0070616_1394 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.882 |
SCL17906.1 | kmo-2 | GA0070616_1385 | GA0070616_1393 | Aminocarboxymuconate-semialdehyde decarboxylase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.950 |
SCL17906.1 | kynA | GA0070616_1385 | GA0070616_1395 | Aminocarboxymuconate-semialdehyde decarboxylase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.741 |
SCL17906.1 | kynU-3 | GA0070616_1385 | GA0070616_1394 | Aminocarboxymuconate-semialdehyde decarboxylase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.937 |
SCL17906.1 | nbaC | GA0070616_1385 | GA0070616_1386 | Aminocarboxymuconate-semialdehyde decarboxylase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.993 |
SCL22403.1 | SCL13003.1 | GA0070616_2530 | GA0070616_0095 | Alpha/beta hydrolase family protein. | Tryptophan 2,3-dioxygenase. | 0.775 |
SCL22403.1 | kmo-2 | GA0070616_2530 | GA0070616_1393 | Alpha/beta hydrolase family protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.407 |
SCL22403.1 | kynA | GA0070616_2530 | GA0070616_1395 | Alpha/beta hydrolase family protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.774 |
SCL22403.1 | kynU | GA0070616_2530 | GA0070616_0219 | Alpha/beta hydrolase family protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.830 |
SCL22403.1 | kynU-2 | GA0070616_2530 | GA0070616_0533 | Alpha/beta hydrolase family protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.831 |
SCL22403.1 | kynU-3 | GA0070616_2530 | GA0070616_1394 | Alpha/beta hydrolase family protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.776 |
SCL25475.1 | SCL13003.1 | GA0070616_3112 | GA0070616_0095 | Selenocysteine lyase/Cysteine desulfurase. | Tryptophan 2,3-dioxygenase. | 0.749 |
SCL25475.1 | kynA | GA0070616_3112 | GA0070616_1395 | Selenocysteine lyase/Cysteine desulfurase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.737 |
SCL25475.1 | kynU | GA0070616_3112 | GA0070616_0219 | Selenocysteine lyase/Cysteine desulfurase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.611 |