STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbWSerine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). (157 aa)    
Predicted Functional Partners:
KON85683.1
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
KON85685.1
Metal ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.990
KON85686.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.984
KON85682.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.972
KON85688.1
RsbR protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.961
KON90176.1
RsbT antagonist protein RsbS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.960
KON87167.1
Sporulation sigma factor SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.950
KON90261.1
Anti-sigma F factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.944
KON89898.1
RsbT co-antagonist protein RsbRB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.873
KON89804.1
Sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.862
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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