Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KON85740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)    
Predicted Functional Partners:
KON89780.1
Cysteine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.920
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
   
    0.838
KON86056.1
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.830
KON85683.1
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.828
KON85500.1
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.773
corA
Metal transporter; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
   
    0.767
KON89831.1
Mg2+ transporter protein, CorA-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.767
KON89804.1
Sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.664
KON86100.1
Glucose starvation-inducible protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.638
KON89898.1
RsbT co-antagonist protein RsbRB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.638
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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