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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KON85866.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)    
Predicted Functional Partners:
KON87533.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.922
KON85865.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.876
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.856
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.831
KON85868.1
Stage VI sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.821
KON87480.1
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.810
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
 0.810
KON85867.1
Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.803
KON87242.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.775
KON86020.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.747
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.