Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pepAAminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (500 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.878
KON90267.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.872
KON85851.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.869
KON86689.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.869
KON88434.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.862
KON87276.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.859
KON86518.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.858
KON86074.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.811
KON86302.1
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.780
KON89769.1
Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.773
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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