Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KON90235.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)    
Predicted Functional Partners:
KON86731.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.659
KON89203.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.633
KON86801.1
Sigma-w pathway protein ysdB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.618
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
     
 0.598
KON86512.1
Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
KON87271.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.569
KON86845.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.508
KON86412.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.500
KON89598.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.467
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.462
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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