Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KON86785.1Membrane protein; Probably functions as a manganese efflux pump. (211 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.931
KON87093.1
Stage III sporulation protein AE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
KON87006.1
Stage IV sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.718
mutM
5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
    0.715
KON86944.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.711
KON86793.1
Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.678
KON87109.1
Peptidase S55; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.678
KON89174.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.677
KON87095.1
Stage III sporulation protein AG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.673
KON90396.1
Dipicolinate synthase subunit A; Catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.669
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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