Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KON86960.1RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (238 aa)    
Predicted Functional Partners:
KON87110.1
Chemotaxis protein CheY; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.813
KON87109.1
Peptidase S55; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.781
KON87227.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.773
KON89395.1
Stage V sporulation protein AEB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
KON89396.1
SpoVAD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.767
KON86153.1
Stage III sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.766
KON89397.1
Stage V sporulation protein AC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.766
KON85864.1
Spore coat protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.756
KON90306.1
Spore gernimation protein GerA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.754
KON88189.1
Spore gernimation protein GerA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.753
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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