Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KON87778.1HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)    
Predicted Functional Partners:
KON85689.1
PemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system.
   
    0.727
KON87780.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.594
KON87779.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
KON87781.1
Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.468
KON87292.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.431
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
    0.418
KON88487.1
D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.400
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
Server load: low (10%) [HD]