STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KON89414.1Dithiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)    
Predicted Functional Partners:
KON89413.1
Globin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.959
spxA-2
ArsR family transcriptional regulator; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
 
 0.887
spxA
ArsR family transcriptional regulator; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
   
 
 0.861
KON90209.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family.
   
   0.840
KON88415.1
Globin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.805
KON87046.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.705
KON89430.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.700
KON87425.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.696
KON86703.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0354 family.
  
     0.694
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.