Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (422 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.997
kynB
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
 
 
 0.997
KON88583.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
  
  0.933
KON88626.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
   
 
  0.860
KON88767.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
   
 
  0.860
KON88725.1
NADH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.811
KON88727.1
4-hydroxyphenylacetate 3-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.811
KON88106.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.739
KON88753.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.610
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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