STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRZ16439.1Phosphomethylpyrimidine kinase. (278 aa)    
Predicted Functional Partners:
CRZ14259.1
Tena/thi-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
 0.999
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
 
 0.998
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.998
CRZ16440.1
Alpha/beta hydrolase superfamily enzyme, hydrolase.
  
    0.959
thiS
Sulfur carrier protein ThiS.
 
 
  0.902
CRZ16797.1
Phosphomethylpyrimidine kinase.
  
  
 
0.896
thiL
Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
  
 0.816
CRZ16441.1
Hypothetical protein.
       0.775
CRZ17155.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.744
CRZ15565.1
Molybdopterin biosynthesis-like protein MoeZ.
 
  
 0.733
Your Current Organism:
Mycolicibacterium neworleansense
NCBI taxonomy Id: 146018
Other names: ATCC 49404, DSM 44679, JCM 15659, M. neworleansense, Mycobacterium genomospecies 2, Mycobacterium neworleansense, Mycobacterium neworleansense Schinsky et al. 2004, Mycolicibacterium neworleansense (Schinsky et al. 2004) Gupta et al. 2018, strain W6705
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