STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRZ18962.16-phosphogluconate dehydrogenase protein. (295 aa)    
Predicted Functional Partners:
mmsA_2
Methylmalonate-semialdehyde dehydrogenase.
 
 
  0.899
mmsA_1
Methylmalonate-semialdehyde dehydrogenase.
 
 
  0.895
CRZ13632.1
acyl-CoA oxidase.
   
 
  0.871
CRZ18437.1
propionate--CoA ligase.
  
 
  0.867
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.865
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.862
CRZ18777.1
3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.851
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.845
CRZ18699.1
AMP-dependent synthetase/ligase.
  
 
  0.845
CRZ13380.1
Acetyl-/propionyl-coenzyme A carboxylase subunit alpha.
  
 
  0.835
Your Current Organism:
Mycolicibacterium neworleansense
NCBI taxonomy Id: 146018
Other names: ATCC 49404, DSM 44679, JCM 15659, M. neworleansense, Mycobacterium genomospecies 2, Mycobacterium neworleansense, Mycobacterium neworleansense Schinsky et al. 2004, Mycolicibacterium neworleansense (Schinsky et al. 2004) Gupta et al. 2018, strain W6705
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.