STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCB_2606HAD-superfamily hydrolase. (301 aa)    
Predicted Functional Partners:
RMCB_2605
MaoC-like dehydratase; Belongs to the UPF0336 family.
  
    0.803
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
 
 
 0.786
RMCB_6071
Phosphatidylinositol synthase pgsA1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.780
RMCB_5381
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.763
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.718
RMCB_4336
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.718
RMCB_0639
Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase.
    
 0.716
RMCB_5240
Phosphatidylglycerophosphate synthase pgsA3; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.716
RMCB_4517
Cystathionine beta-synthase CBS.
    
 0.713
RMCB_1293
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.
    
 0.705
Your Current Organism:
Mycolicibacterium brisbanense
NCBI taxonomy Id: 146020
Other names: ATCC 49938, CCUG 47584, DSM 44680, JCM 15654, M. brisbanense, Mycobacterium brisbanense, Mycobacterium brisbanense Schinsky et al. 2004, Mycobacterium genomospecies 4, Mycolicibacterium brisbanense (Schinsky et al. 2004) Gupta et al. 2018, strain W6743
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