STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCB_3466Excalibur domain-containing protein. (63 aa)    
Predicted Functional Partners:
RMCB_1430
Competence damage-inducible protein A; Belongs to the CinA family.
    
  0.743
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.705
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.703
RMCB_1281
Membrane-bound C-5 sterol desaturase erg3.
   
    0.562
deaD
Cold-shock deaD-box protein A deaD, ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
    
 0.548
RMCB_3465
Histone-lysine N-methyltransferase, H3 lysine-4 specific.
       0.548
RMCB_3467
ABC-type multidrug transport system, ATPase and permease component.
   
   0.548
RMCB_3784
ATP-dependent RNA helicase.
    
 0.548
RMCB_5988
ATP-dependent RNA helicase rhlE; Belongs to the DEAD box helicase family.
    
 0.548
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.529
Your Current Organism:
Mycolicibacterium brisbanense
NCBI taxonomy Id: 146020
Other names: ATCC 49938, CCUG 47584, DSM 44680, JCM 15654, M. brisbanense, Mycobacterium brisbanense, Mycobacterium brisbanense Schinsky et al. 2004, Mycobacterium genomospecies 4, Mycolicibacterium brisbanense (Schinsky et al. 2004) Gupta et al. 2018, strain W6743
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.