STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCB_5109CBS domain-containing protein. (151 aa)    
Predicted Functional Partners:
RMCB_5110
Arsenic-transport integral membrane protein.
 
    0.964
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.957
RMCB_3129
Uncharacterized protein.
   
 0.925
RMCB_6569
Uncharacterized protein.
   
 0.864
atpH
ATP synthase subunit H; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family.
  
 
 0.847
RMCB_4336
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.832
RMCB_3101
Uncharacterized protein.
 
 
 
 0.774
guaB
Inosine-5-monophosphate dehydrogenase guaB2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.764
RMCB_5994
Molybdopterin biosynthesis-like protein MoeZ.
  
 
 0.741
RMCB_0225
Zn-dependent hydrolase, glyoxylase.
   
 
 0.716
Your Current Organism:
Mycolicibacterium brisbanense
NCBI taxonomy Id: 146020
Other names: ATCC 49938, CCUG 47584, DSM 44680, JCM 15654, M. brisbanense, Mycobacterium brisbanense, Mycobacterium brisbanense Schinsky et al. 2004, Mycobacterium genomospecies 4, Mycolicibacterium brisbanense (Schinsky et al. 2004) Gupta et al. 2018, strain W6743
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