KCV83679.1 protein (Actibacterium atlanticum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KCV83679.1

Hypothetical protein. (379 aa)

Predicted Functional Partners:

KCV83669.1

0.998

KCV83682.1

0.998

KCV83670.1

0.995

KCV83683.1

0.991

KCV83680.1

0.962

KCV83676.1

0.958

KCV83677.1

0.948

KCV83671.1

0.937

KCV83673.1

0.937

KCV83674.1

0.937

Your Current Organism:

Actibacterium atlanticum

NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KCV83669.1	KCV83670.1	ATO10_02875	ATO10_02880	COG3497 Phage tail sheath protein FI.	Phage tail region protein.	0.998
KCV83669.1	KCV83671.1	ATO10_02875	ATO10_02885	COG3497 Phage tail sheath protein FI.	Hypothetical protein.	0.934
KCV83669.1	KCV83673.1	ATO10_02875	ATO10_02895	COG3497 Phage tail sheath protein FI.	Hypothetical protein.	0.934
KCV83669.1	KCV83674.1	ATO10_02875	ATO10_02900	COG3497 Phage tail sheath protein FI.	COG0464 ATPases of the AAA+ class.	0.934
KCV83669.1	KCV83676.1	ATO10_02875	ATO10_02910	COG3497 Phage tail sheath protein FI.	Hypothetical protein.	0.956
KCV83669.1	KCV83677.1	ATO10_02875	ATO10_02915	COG3497 Phage tail sheath protein FI.	Hypothetical protein.	0.923
KCV83669.1	KCV83679.1	ATO10_02875	ATO10_02925	COG3497 Phage tail sheath protein FI.	Hypothetical protein.	0.998
KCV83669.1	KCV83680.1	ATO10_02875	ATO10_02930	COG3497 Phage tail sheath protein FI.	COG3501 Uncharacterized protein conserved in bacteria.	0.935
KCV83669.1	KCV83682.1	ATO10_02875	ATO10_02940	COG3497 Phage tail sheath protein FI.	COG3628 Phage baseplate assembly protein W.	0.998
KCV83669.1	KCV83683.1	ATO10_02875	ATO10_02945	COG3497 Phage tail sheath protein FI.	Putative phage tail region protein; COG3299 Uncharacterized homolog of phage Mu protein gp47.	0.996
KCV83670.1	KCV83669.1	ATO10_02880	ATO10_02875	Phage tail region protein.	COG3497 Phage tail sheath protein FI.	0.998
KCV83670.1	KCV83671.1	ATO10_02880	ATO10_02885	Phage tail region protein.	Hypothetical protein.	0.945
KCV83670.1	KCV83673.1	ATO10_02880	ATO10_02895	Phage tail region protein.	Hypothetical protein.	0.945
KCV83670.1	KCV83674.1	ATO10_02880	ATO10_02900	Phage tail region protein.	COG0464 ATPases of the AAA+ class.	0.945
KCV83670.1	KCV83676.1	ATO10_02880	ATO10_02910	Phage tail region protein.	Hypothetical protein.	0.963
KCV83670.1	KCV83677.1	ATO10_02880	ATO10_02915	Phage tail region protein.	Hypothetical protein.	0.934
KCV83670.1	KCV83679.1	ATO10_02880	ATO10_02925	Phage tail region protein.	Hypothetical protein.	0.995
KCV83670.1	KCV83680.1	ATO10_02880	ATO10_02930	Phage tail region protein.	COG3501 Uncharacterized protein conserved in bacteria.	0.947
KCV83670.1	KCV83682.1	ATO10_02880	ATO10_02940	Phage tail region protein.	COG3628 Phage baseplate assembly protein W.	0.993
KCV83670.1	KCV83683.1	ATO10_02880	ATO10_02945	Phage tail region protein.	Putative phage tail region protein; COG3299 Uncharacterized homolog of phage Mu protein gp47.	0.994

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070995

NADPH oxidation

2 of 8

3.19

2.26

0.0023

GO:0006805

Xenobiotic metabolic process

3 of 114

2.21

2.09

0.0022

GO:0062012

Regulation of small molecule metabolic process

3 of 184

2.0

1.96

0.0023

GO:0019216

Regulation of lipid metabolic process

3 of 192

1.99

1.95

0.0023

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004499

N,N-dimethylaniline monooxygenase activity

3 of 9

3.32

5.32

5.44e-07

GO:0050661

NADP binding

3 of 48

2.59

3.83

1.72e-05

GO:0050660

Flavin adenine dinucleotide binding

3 of 84

2.35

3.23

6.55e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9570

Flavin-binding monooxygenase-like, and NADPH oxidation

3 of 5

3.57

5.72

2.08e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-217271

FMO oxidises nucleophiles

2 of 8

3.19

2.47

0.0013

MAP-211945

Phase I - Functionalization of compounds

3 of 207

1.95

2.08

0.0013

MAP-211859

Biological oxidations

3 of 315

1.77

1.74

0.0027

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0274

FAD

3 of 59

2.5

3.89

1.14e-05

KW-0503

Monooxygenase

3 of 95

2.29

3.61

1.53e-05

KW-0521

NADP

2 of 39

2.5

2.48

0.00092

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00743

Flavin-binding monooxygenase-like

2 of 2

3.79

3.16

0.00022

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