STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCV82477.1COG3145 Alkylated DNA repair protein. (213 aa)    
Predicted Functional Partners:
KCV81380.1
AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
 
  
 0.710
KCV82478.1
Putative NAD-specific glutamate dehydrogenase.
       0.620
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
   0.505
KCV80964.1
Magnesium transporter; Acts as a magnesium transporter.
      0.481
KCV83578.1
DNA-glycosylase family protein; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.
     
 0.423
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.414
Your Current Organism:
Actibacterium atlanticum
NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10
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