STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCV81480.1Glutamate--ammonia ligase; COG0174 Glutamine synthetase. (451 aa)    
Predicted Functional Partners:
KCV82390.1
Glutamate synthase (NADPH) large subunit; COG0067 Glutamate synthase domain 1.
  
 
 0.967
KCV81481.1
Gamma-glutamylputrescine oxidoreductase PuuB; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 
 0.966
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.855
KCV82616.1
Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.853
KCV81479.1
COG0518 GMP synthase - Glutamine amidotransferase domain.
 
   
 0.829
KCV82807.1
Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  0.811
KCV83137.1
Gamma-glutamyl-gamma-aminobutyrate hydrolase; COG2071 Predicted glutamine amidotransferases.
 
 
 0.750
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.728
KCV81435.1
Putative modular PKS system; COG2070 Dioxygenases related to 2-nitropropane dioxygenase.
    
 0.725
KCV82391.1
Dihydropyrimidine dehydrogenase subunit A; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.720
Your Current Organism:
Actibacterium atlanticum
NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10
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