STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
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[Homology]
Score
hypAHydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
KCV81290.1
Hydrogenase nickel incorporation protein HypB; COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase.
 
 
 0.988
KCV81293.1
Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor; Belongs to the HypD family.
 
  
 0.966
KCV81294.1
Hydrogenase expression/formation protein HypE; COG0309 Hydrogenase maturation factor.
 
  
 0.959
KCV81288.1
Hydrogenase expression/formation protein HupK; COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.
  
 
 0.954
KCV81292.1
Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.
 
  
 0.951
KCV81286.1
HupH hydrogenase expression protein.
 
  
 0.941
KCV81280.1
COG0374 Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.940
KCV81287.1
COG1773 Rubredoxin.
 
  
 0.937
KCV81285.1
Hydrogenase-1 expression HyaE; COG3118 Thioredoxin domain-containing protein; Belongs to the HupG/HyaE family.
 
   
 0.935
KCV81283.1
Hydrogenase expression/formation protein; COG0680 Ni,Fe-hydrogenase maturation factor.
 
  
 0.915
Your Current Organism:
Actibacterium atlanticum
NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10
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