STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCV81292.1Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor. (96 aa)    
Predicted Functional Partners:
KCV81293.1
Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor; Belongs to the HypD family.
 
 
 0.999
KCV81294.1
Hydrogenase expression/formation protein HypE; COG0309 Hydrogenase maturation factor.
 
 
 0.998
KCV81290.1
Hydrogenase nickel incorporation protein HypB; COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase.
 
  
 0.987
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.951
KCV81278.1
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.915
KCV81287.1
COG1773 Rubredoxin.
 
  
 0.891
KCV81288.1
Hydrogenase expression/formation protein HupK; COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.
  
 
 0.877
KCV81285.1
Hydrogenase-1 expression HyaE; COG3118 Thioredoxin domain-containing protein; Belongs to the HupG/HyaE family.
 
  
 0.864
KCV81277.1
Hydrogen:quinone oxidoreductase; COG0374 Ni,Fe-hydrogenase I large subunit.
 
 
 0.858
KCV81286.1
HupH hydrogenase expression protein.
  
  
 0.857
Your Current Organism:
Actibacterium atlanticum
NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10
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