STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCV81065.1COG0789 Predicted transcriptional regulators. (133 aa)    
Predicted Functional Partners:
KCV81066.1
Heavy metal-transporting ATPase; COG2217 Cation transport ATPase.
 
  
 0.813
KCV81067.1
COG2608 Copper chaperone.
 
  
 0.676
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.646
KCV83129.1
Heat shock protein DnaJ domain-containing protein; COG2214 DnaJ-class molecular chaperone.
  
 
 0.621
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.621
KCV82873.1
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
     
 0.607
KCV81643.1
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
     
 0.607
KCV82522.1
COG0281 Malic enzyme.
    
  0.581
KCV82048.1
COG0281 Malic enzyme.
    
  0.581
KCV81889.1
PAS sensor protein; COG0642 Signal transduction histidine kinase.
   
 0.571
Your Current Organism:
Actibacterium atlanticum
NCBI taxonomy Id: 1461693
Other names: A. atlanticum, Actibacterium atlanticum Li et al. 2015, Actibacterium sp. 22II-S11-z10, LMG 27158, LMG:27158, MCCC 1A09298, strain 22II-S11-z10
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