STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SER41192.1DNA replication protein. (240 aa)    
Predicted Functional Partners:
nth
Endonuclease-3; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 0.947
SES02844.1
Primosomal protein DnaI.
 
  
 0.814
SES02821.1
Replicative DNA helicase loader DnaB.
  
   
 0.774
SES00280.1
Competence protein ComFA.
  
     0.707
SES24049.1
Regulator of replication initiation timing; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.694
SER41333.1
Protein of unknown function.
 
     0.674
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
     0.666
SER79720.1
Hypothetical protein.
  
     0.649
asnS
asparaginyl-tRNA synthetase.
  
    0.645
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.636
Your Current Organism:
Salisediminibacterium haloalkalitolerans
NCBI taxonomy Id: 1464123
Other names: CGMCC 1.12818, KCTC 33414, S. haloalkalitolerans, Salisediminibacterium haloalkalitolerans Sultanpuram et al. 2015, Salisediminibacterium sp. 10nlg, strain 10nlg
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.