STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa)    
Predicted Functional Partners:
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.999
SFP91520.1
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 0.999
SFP91573.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.998
SFP91311.1
Ketol-acid reductoisomerase.
  
 0.994
SFP91422.1
Acetolactate synthase, large subunit.
 
 
 0.919
ilvD
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.911
SFP66714.1
Isocitrate dehydrogenase.
 0.903
SFQ34751.1
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.887
SFP91400.1
Acetolactate synthase, small subunit.
 
  
 0.881
SFP90196.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.873
Your Current Organism:
Parafilimonas terrae
NCBI taxonomy Id: 1465490
Other names: DSM 28286, Filimonas sp. 5GHs7-2, KACC 17343, P. terrae, Parafilimonas terrae Kim et al. 2014, strain 5GHs7-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.