STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM66356.1Diadenylate cyclase; Belongs to the DisA family. (360 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.954
ispDF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
    0.602
SDM66542.1
Uncharacterized conserved protein YacL, contains PIN and TRAM domains.
  
  
 0.589
SDN02081.1
MazG-like family protein.
  
     0.569
mcsB
Protein arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family.
  
    0.557
SDM66217.1
Protein-arginine kinase activator protein McsA.
  
    0.550
SDL87706.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
   
    0.515
SDL90175.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
   
    0.515
SDN06078.1
TIGR00375 family protein.
   
    0.515
SDM66283.1
ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.
  
    0.480
Your Current Organism:
Dendrosporobacter quercicolus
NCBI taxonomy Id: 146817
Other names: ATCC 25974, Clostridium quercicolum, D. quercicolus
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