node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM75678.1 | SDM88129.1 | SAMN04488502_10740 | SAMN04488502_10893 | Flagellar hook-associated protein 3 FlgL. | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.611 |
SDM75678.1 | fliE | SAMN04488502_10740 | SAMN04488502_101718 | Flagellar hook-associated protein 3 FlgL. | Flagellar hook-basal body complex protein FliE. | 0.946 |
SDM75678.1 | gyrA | SAMN04488502_10740 | SAMN04488502_1109 | Flagellar hook-associated protein 3 FlgL. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.733 |
SDM87883.1 | SDM88129.1 | SAMN04488502_10887 | SAMN04488502_10893 | Flagellar hook-associated protein 3 FlgL. | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.889 |
SDM87883.1 | fliE | SAMN04488502_10887 | SAMN04488502_101718 | Flagellar hook-associated protein 3 FlgL. | Flagellar hook-basal body complex protein FliE. | 0.943 |
SDM87883.1 | gyrA | SAMN04488502_10887 | SAMN04488502_1109 | Flagellar hook-associated protein 3 FlgL. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.733 |
SDM88129.1 | SDM75678.1 | SAMN04488502_10893 | SAMN04488502_10740 | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Flagellar hook-associated protein 3 FlgL. | 0.611 |
SDM88129.1 | SDM87883.1 | SAMN04488502_10893 | SAMN04488502_10887 | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Flagellar hook-associated protein 3 FlgL. | 0.889 |
SDM88129.1 | fliE | SAMN04488502_10893 | SAMN04488502_101718 | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Flagellar hook-basal body complex protein FliE. | 0.935 |
SDM88129.1 | gyrA | SAMN04488502_10893 | SAMN04488502_1109 | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.736 |
aroB | gyrA | SAMN04488502_101333 | SAMN04488502_1109 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.783 |
aroB | ispH | SAMN04488502_101333 | SAMN04488502_101222 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.489 |
fliE | SDM75678.1 | SAMN04488502_101718 | SAMN04488502_10740 | Flagellar hook-basal body complex protein FliE. | Flagellar hook-associated protein 3 FlgL. | 0.946 |
fliE | SDM87883.1 | SAMN04488502_101718 | SAMN04488502_10887 | Flagellar hook-basal body complex protein FliE. | Flagellar hook-associated protein 3 FlgL. | 0.943 |
fliE | SDM88129.1 | SAMN04488502_101718 | SAMN04488502_10893 | Flagellar hook-basal body complex protein FliE. | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.935 |
fliE | gyrA | SAMN04488502_101718 | SAMN04488502_1109 | Flagellar hook-basal body complex protein FliE. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.769 |
folD | gyrA | SAMN04488502_101889 | SAMN04488502_1109 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.804 |
folD | gyrB | SAMN04488502_101889 | SAMN04488502_11047 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.513 |
gyrA | SDM75678.1 | SAMN04488502_1109 | SAMN04488502_10740 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Flagellar hook-associated protein 3 FlgL. | 0.733 |
gyrA | SDM87883.1 | SAMN04488502_1109 | SAMN04488502_10887 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Flagellar hook-associated protein 3 FlgL. | 0.733 |