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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
serBPhosphoserine phosphatase SerB. (418 aa)    
Predicted Functional Partners:
serC
Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.977
glyA1
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.939
WM42_2486
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.923
WM42_2581
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.923
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 
 0.915
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.906
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
  0.900
cysE
Serine O-acetyltransferase.
    
 0.851
WM42_1909
peptidyl-tRNA hydrolase PTH2 family protein.
       0.822
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
     
  0.800
Your Current Organism:
Corynebacterium simulans
NCBI taxonomy Id: 146827
Other names: ATCC BAA-15, C. simulans, CCUG 43305, CIP 106488, Corynebacterium simulans Wattiau et al. 2000, Corynebacterium sp. UCL301, Corynebacterium sp. UCL553, Corynebacterium sp. UCL557, DSM 44415, JCM 12107, UCL 553, strain Co 553
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