STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LI90_266Hypothetical protein. (1001 aa)    
Predicted Functional Partners:
LI90_268
Hypothetical protein.
 
     0.957
LI90_269
Helicase domain protein.
 
     0.949
LI90_267
Hypothetical protein.
       0.796
LI90_2910
DUF324 domain-containing protein.
  
     0.571
LI90_2908
Uncharacterized protein.
  
     0.550
LI90_4305
Metal dependent phosphohydrolase.
  
     0.533
LI90_2911
DUF324 domain-containing protein.
  
     0.516
cas1-2
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
     0.515
LI90_4306
CRISPR-associated autoregulator; DevR family.
  
     0.512
LI90_4308
Hypothetical protein.
  
     0.490
Your Current Organism:
Streptomyces thermoautotrophicus
NCBI taxonomy Id: 1469144
Other names: DSM 41605, LMG 19855, LMG:19855, NBRC 101056, S. thermoautotrophicus, strain UBT1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.