STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSP05995.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (240 aa)    
Predicted Functional Partners:
OSP05994.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
OSP05991.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.734
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.678
OSP02306.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.678
OSP05992.1
Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.656
OSP05993.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.609
OSP05987.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.581
OSP05997.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.579
OSP05998.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.579
OSP05988.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.542
Your Current Organism:
Streptomyces griseofuscus
NCBI taxonomy Id: 146922
Other names: ATCC 23916, BCRC 10483, CBS 837.68, CCRC 10483, CCRC:10483, CECT 3307, DSM 40191, IFO 12870, IMET 42068, ISP 5191, JCM 4276, JCM 4641, KACC 20083, NBRC 12870, NCIMB 9821, NRRL B-5429, NRRL-ISP 5191, S. griseofuscus, Streptomyces griseifuscus
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