STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSP02590.1Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (162 aa)    
Predicted Functional Partners:
OSP02589.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.930
OSP01108.1
DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.744
OSP02806.1
DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.744
OSP02591.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.636
OSP07033.1
Alpha-ketoglutarate-dependent dioxygenase AlkB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.628
OSP01347.1
YajQ family cyclic di-GMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0234 family.
       0.579
rsgA-2
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
       0.579
OSP03518.1
Proline hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.579
OSP01727.1
3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.502
OSP03949.1
RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
   0.474
Your Current Organism:
Streptomyces griseofuscus
NCBI taxonomy Id: 146922
Other names: ATCC 23916, BCRC 10483, CBS 837.68, CCRC 10483, CCRC:10483, CECT 3307, DSM 40191, IFO 12870, IMET 42068, ISP 5191, JCM 4276, JCM 4641, KACC 20083, NBRC 12870, NCIMB 9821, NRRL B-5429, NRRL-ISP 5191, S. griseofuscus, Streptomyces griseifuscus
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