STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDD76_11198Unannotated protein. (374 aa)    
Predicted Functional Partners:
EDD76_11199
Unannotated protein.
 
 0.987
EDD76_104214
Unannotated protein.
 
 
 0.927
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.918
EDD76_11176
Unannotated protein.
  
    0.790
EDD76_102227
Unannotated protein.
  
  
 0.787
EDD76_102291
Unannotated protein.
 
  
 0.740
EDD76_114102
Unannotated protein; Belongs to the UPF0102 family.
 
    0.739
EDD76_103289
Unannotated protein.
 
   
 0.732
recA
Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.730
EDD76_1144
Unannotated protein.
  
  
 0.680
Your Current Organism:
Kineothrix alysoides
NCBI taxonomy Id: 1469948
Other names: ATCC TSD-26, Clostridium sp. KNHs209, DSM 100556, K. alysoides, Kineothrix alysoides Haas and Blanchard 2017, Lachnospiraceae bacterium KNHs209, strain KNHs209
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.