STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMO69812.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.793
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.784
AMO69809.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.763
AMO69813.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.576
AMO69803.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.423
AZF00_16215
TonB-dependent receptor; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.413
AMO68556.1
Transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.402
AMO69808.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.400
Your Current Organism:
Zhongshania aliphaticivorans
NCBI taxonomy Id: 1470434
Other names: JCM 30138, KACC 18120, Spongiibacter sp. SM-2, Z. aliphaticivorans, Zhongshania aliphaticivorans Lo et al. 2014, strain SM-2, strain SM2
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