STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHJ65793.1hydroxymethylglutaryl-CoA lyase. (285 aa)    
Predicted Functional Partners:
SHJ65841.1
methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.991
SHJ65706.1
3-methylcrotonoyl-CoA carboxylase, alpha subunit.
 
 0.963
SHJ65668.1
3-methylcrotonyl-CoA carboxylase beta subunit.
 0.955
SHK02819.1
3-oxoacid CoA-transferase subunit A.
  
 
 0.905
leuD
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.901
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.901
SHK02783.1
3-oxoacid CoA-transferase subunit B.
  
 
 0.893
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.883
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.873
SHI88204.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.865
Your Current Organism:
Pseudopelagicola gijangensis
NCBI taxonomy Id: 1470563
Other names: CECT 8540, DSM 100564, KCTC 42049, P. gijangensis, Pseudopelagicola gijangensis Kim et al. 2014, Rhodobacteraceae bacterium YSS-7, strain YSS-7
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