STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0W44_12945Ornithine--oxo-acid transaminase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (139 aa)    
Predicted Functional Partners:
AQS55442.1
Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
  
     0.764
AQS56534.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
     
 0.738
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.599
AQS57492.1
CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.579
AQS55845.1
Thioredoxin peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.572
AQS55885.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.564
clpP
ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.513
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
  
    0.509
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.482
mntR
Manganese transport transcriptional regulator; Central regulator of manganese homeostasis. Belongs to the DtxR/MntR family.
  
  
 0.459
Your Current Organism:
Novibacillus thermophilus
NCBI taxonomy Id: 1471761
Other names: Bacillales bacterium SG-1, Bacillales bacterium SG-2, CGMCC 1.12771, KCTC 33118, N. thermophilus, Novibacillus thermophilus Yang et al. 2015, strain SG-1
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